Solving Genome Puzzles

The Computational Mathematics Seminar presents talks on the development of computational science & mathematics, including the mathematical / computational modelling of complex systems including their implementation issues and theoretical aspects.

schedule Date & time
Date/time
19 Jul 2022 4:00pm - 19 Jul 2022 5:00pm
person Speaker

Speakers

Yu Lin, ANU
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Description

Abstract:

Genomics sequencing has created opportunities and challenges to gain new insights into biology and biomedical research. Genome sequencing data usually consists of millions or billions of short DNA sequences, called reads, that are randomly drawn from genomes. Genome assembly is to put reads back together into a single genome, like solving a giant jigsaw puzzle. While the problem of genome assembly remains computationally challenging, metagenomic analysis aims to resolve the composition of a mixture of genomes, like solving mixed jigsaw puzzles simultaneously. In this talk, we will present how to design graph models and algorithms to address these emerging challenges.

Bio:

Yu Lin is a Senior Lecturer and runs the Computational Genomics Group at the School of Computing, the Australian National University. Prior to this, he was a postdoctoral fellow at the Department of Computer Science and Engineering, University of California San Diego (UCSD). He received his PhD in Computer Science from École Polytechnique Fédérale de Lausanne (EPFL), Switzerland. His research focuses on computational biology and bioinformatics, and he has been working on models and algorithms for genome assembly, metagenomics and comparative genomics. In 2020, he received the Outstanding Contribution by an Early Career Researcher Award from the Australian Bioinformatics and Computational Biology Society.

Zoom Details:

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Topic: Mathematics and Computational Sciences Seminar Series 
Time: This is a recurring meeting Meet anytime

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Location

Seminar Room 1.33

Hanna Neumann Building #145

Science Road

The Australian National University

Canberra ACT 2600 

-35.275387198178, 149.11925554276